Transdermal contraceptive delivery system and process

Details Transdermal contraceptive delivery system and process Transdermal contraceptive delivery system and process

1996-04-24

1998-06-09

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424448, 514946, 514947, A61F 1300

Patent

active

057629560

ABSTRACT:
A transdermal contraceptive delivery system (TCDS) for fertility control in women is described comprising a backing layer, an adjoining layer of a solid absorption adhesive polymer matrix in which minimum effective daily doses of an estrogen and a progestin are dispersed and released for transdermal absorption. Presently preferred is use of the natural estrogen, 17-beta-estradiol, and the synthetic progestin, levonorgestrel. Along with these two steroidal contraceptive agents, a combination of several chemical skin permeation enhancing agents, blended at specific weight ratios, are homogeneously dispersed in the adhesive polymer matrix. The invention also provides a process of fertility control utilizing the transdermal contraceptive delivery system.

REFERENCES:
patent: 4818540 (1989-04-01), Chien et al.
patent: 4906169 (1990-03-01), Chien et al.
patent: 4906475 (1990-03-01), Kim
patent: 5296230 (1994-03-01), Chien et al.
patent: 5314694 (1994-05-01), Gale

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