Transdermal administration of fentanyl and device therefor

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 14, 424 16, 424 19, 424 22, 514316, 514329, 604896, 604897, 604 93, 604304, 604307, A01N 2524, A61K 970

Patent

active

045885800

ABSTRACT:
Transdermal delivery systems for delivery of fentanyl and its analgetically effective derivatives for extended periods of time are disclosed which deliver the base form of the drug at a rate of from 0.5 to 10 .mu.g/cm.sup.2 /hr for a substantial portion of their useful life. The systems can be from 5-100 cm.sup.2 in releasing surface and preferably employ an in-line amine resistant adhesive. Preferred rate controlled systems utilize an aqueous ethanolic gel to minimize drug content.

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Isaacs, "A Safer Way to Take Your Medicine", Parade Magazine, May 12, 1985, p. 8.
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