Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-11
1994-12-20
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514411, 514567, 514570, 514653, 514947, A61K 31485
Patent
active
053746457
ABSTRACT:
A composition for the transdermal administration of ionic pharmaceutically active agents comprising the active agent along with a suitable counter ion, water, and isopropanol, at an adjusted pH is disclosed. Also disclosed are transdermal systems which employ this composition and methods of transdermally administering such agents therewith. The main advantage achieved is improved flux rates of active agent over other systems.
REFERENCES:
patent: 3551554 (1970-12-01), Herschler
patent: 5064654 (1991-11-01), Berner et al.
patent: 5073539 (1991-12-01), Mazzenga et al.
Friend et al-Journal of Controlled Release, 7 (1988) 243-250.
Chemical Abstracts 11th Coll. Index, vol. 96-105, pp. 8700-8702 Cs, 1982-1986.
Kurihara-Bergstrom Tamie
Liu Puchun
Ciba-Geigy Corporation
Cintins Marianne M.
Fishman Irving M.
Jarvis William R. A.
Kaiser Karen G.
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