Transdermal absorption dosage unit for estradiol and other estro

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424449, 424486, A61F 1302

Patent

active

048836699

ABSTRACT:
This invention relates to a novel transdermal absorption dosage unit comprising a backing layer, an adjoining layer of solid polymer matrix in which estradiol or another steroidal pharmaceutical having estrogenic activity is microdispersed; and a biologically acceptable adhesive means by which the dosage unit adheres to the skin of the subject being administered said estradiol or another said steroidal pharmaceutical and adapted to permit transdermal absorption of said estradiol or another said steroidal pharmaceutical. Additionally, the invention relates to improved estradiol or other estrogenic steroid maintenance therapy.

REFERENCES:
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4053580 (1977-10-01), Chien et al.
patent: 4291014 (1981-09-01), Kieth et al.
patent: 4300820 (1981-11-01), Shah
patent: 4336243 (1982-06-01), Sanvordeker et al.
patent: 4460372 (1984-08-01), Campbell et al.
patent: 4693887 (1987-09-01), Shah

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