Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1986-05-30
1989-11-28
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424449, 424486, A61F 1302
Patent
active
048836699
ABSTRACT:
This invention relates to a novel transdermal absorption dosage unit comprising a backing layer, an adjoining layer of solid polymer matrix in which estradiol or another steroidal pharmaceutical having estrogenic activity is microdispersed; and a biologically acceptable adhesive means by which the dosage unit adheres to the skin of the subject being administered said estradiol or another said steroidal pharmaceutical and adapted to permit transdermal absorption of said estradiol or another said steroidal pharmaceutical. Additionally, the invention relates to improved estradiol or other estrogenic steroid maintenance therapy.
REFERENCES:
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4053580 (1977-10-01), Chien et al.
patent: 4291014 (1981-09-01), Kieth et al.
patent: 4300820 (1981-11-01), Shah
patent: 4336243 (1982-06-01), Sanvordeker et al.
patent: 4460372 (1984-08-01), Campbell et al.
patent: 4693887 (1987-09-01), Shah
Chien Te-Yen
Chien Yie W.
Lee Chia-Shun
Valia Kirti H.
Horne Leon R.
Page Thurman K.
Rutgers The State University of New Jersey
Sinn Leroy G.
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