Transcriptionally-activated AAV inverted terminal repeats...

Details Transcriptionally-activated AAV inverted terminal repeats... Transcriptionally-activated AAV inverted terminal repeats...

2005-08-30

2005-08-30

Mosher, Mary E. (Department: 1648)

Chemistry: molecular biology and microbiology

Vector, per se

C435S325000, C435S235100, C435S440000, C435S455000, C435S456000, C435S457000, C536S023720, C536S024100, C536S023500

Reexamination Certificate

active

06936466

ABSTRACT:
This invention provides transcriptionally-activated AAV ITRs (inverted terminal repeats) which are small and transcriptionally active and uses thereof to optimize the expression of relatively large transgenes packaged in recombinant AAV vectors.

REFERENCES:
patent: 4797368 (1989-01-01), Carter et al.
patent: 5139941 (1992-08-01), Muzyczka et al.
patent: 5252479 (1993-10-01), Srivastava
patent: 5387484 (1995-02-01), Doany et al.
patent: 5587308 (1996-12-01), Carter et al.
patent: 5587508 (1996-12-01), Machida
patent: 5652224 (1997-07-01), Wilson et al.
patent: 5658776 (1997-08-01), Flotte et al.
patent: 5658785 (1997-08-01), Johnson
patent: 5731182 (1998-03-01), Boyce
patent: 5756283 (1998-05-01), Wilson et al.
patent: 5786211 (1998-07-01), Johnson
patent: 5837484 (1998-11-01), Trempe et al.
patent: 5856152 (1999-01-01), Wilson et al.
patent: 5858775 (1999-01-01), Johnson
patent: 5866552 (1999-02-01), Wilson et al.
patent: 5866696 (1999-02-01), Carter et al.
patent: 5871982 (1999-02-01), Wilson et al.
patent: 5871986 (1999-02-01), Boyce
patent: 5872154 (1999-02-01), Wilson et al.
patent: 5989540 (1999-11-01), Carter et al.
patent: 5990279 (1999-11-01), Carter et al.
patent: 6001557 (1999-12-01), Wilson et al.
patent: 6165781 (2000-12-01), Carter et al.
patent: 6174527 (2001-01-01), Wilson et al.
patent: 6183993 (2001-02-01), Boyce et al.
patent: 6187532 (2001-02-01), Wood et al.
patent: 6190887 (2001-02-01), Boyce et al.
patent: 6197527 (2001-03-01), Lynch et al.
patent: 6203975 (2001-03-01), Wilson et al.
patent: 6211160 (2001-04-01), Wilson et al.
patent: 6238914 (2001-05-01), Boyce
patent: 6251677 (2001-06-01), Wilson et al.
patent: 6251957 (2001-06-01), Wilson et al.
patent: 6258595 (2001-07-01), Gao et al.
patent: 6261551 (2001-07-01), Wilson et al.
patent: 6270996 (2001-08-01), Wilson et al.
patent: 6274354 (2001-08-01), Wilson et al.
patent: 6281009 (2001-08-01), Boyce
patent: 6281010 (2001-08-01), Gao et al.
patent: 6338953 (2002-01-01), Boyce et al.
patent: 6338962 (2002-01-01), Boyce
patent: 6346415 (2002-02-01), Feldhaus
patent: 6372208 (2002-04-01), Wilson et al.
patent: 6387368 (2002-05-01), Wilson et al.
patent: 6399370 (2002-06-01), Wilson et al.
patent: 6399385 (2002-06-01), Croyle et al.
patent: 6428988 (2002-08-01), Wilson et al.
patent: 6436392 (2002-08-01), Engelhardt et al.
patent: 6475769 (2002-11-01), Wilson et al.
patent: 6482634 (2002-11-01), Wilson et al.
patent: 6485966 (2002-11-01), Gao et al.
patent: 6537540 (2003-03-01), Burstein et al.
patent: 6541258 (2003-04-01), Allen et al.
patent: 6548286 (2003-04-01), Samulski et al.
patent: 6566118 (2003-05-01), Atkinson et al.
patent: 6596535 (2003-07-01), Carter
patent: 6610290 (2003-08-01), Podsakoff et al.
patent: 6632670 (2003-10-01), Wadsworth et al.
patent: 6642051 (2003-11-01), Lynch et al.
patent: 6759237 (2004-07-01), Wilson et al.
patent: 2001/0006955 (2001-07-01), Wilson et al.
patent: 2002/0001581 (2002-01-01), Lynch et al.
patent: 2002/0032163 (2002-03-01), Wilson et al.
patent: 2002/0037867 (2002-03-01), Wilson et al.
patent: 2002/0081297 (2002-06-01), Wilson et al.
patent: 2002/0127582 (2002-09-01), Atkinson et al.
patent: 2002/0159979 (2002-10-01), Johnson
patent: 2002/0160501 (2002-10-01), Atkinson et al.
patent: 2002/0182182 (2002-12-01), Wilson et al.
patent: 2002/0197237 (2002-12-01), Engelhardt et al.
patent: 2003/0040101 (2003-02-01), Wilosn et al.
patent: 2003/0073232 (2003-04-01), Wilson et al.
patent: 2003/0082145 (2003-05-01), Johnson
patent: 2003/0103939 (2003-06-01), Engelhardt et al.
patent: 2003/0103942 (2003-06-01), Burstein et al.
patent: 2003/0113295 (2003-06-01), Burstein et al.
patent: 2003/0119191 (2003-06-01), Gao et al.
patent: 2003/0175974 (2003-09-01), Allen
patent: 2003/0219735 (2003-11-01), Carter
patent: 2004/0052764 (2004-03-01), Hildinger et al.
patent: 2004/0057931 (2004-03-01), Wilson et al.
patent: 2004/0057932 (2004-03-01), Wilson et al.
patent: 2004/0057933 (2004-03-01), Wilson et al.
patent: 2004/0062752 (2004-04-01), Walsh et al.
patent: WO 93/24641 (1993-12-01), None
patent: WO 93/24641 (1993-12-01), None
patent: WO 95/13365 (1995-05-01), None
patent: WO 95/13392 (1995-05-01), None
patent: WO 95/34670 (1995-12-01), None
patent: WO 96/09074 (1996-03-01), None
patent: WO 96/13597 (1996-05-01), None
patent: WO 96/13598 (1996-05-01), None
patent: WO 96/17947 (1996-06-01), None
patent: WO 96/26285 (1996-08-01), None
patent: WO 96/26286 (1996-08-01), None
patent: WO 96/39530 (1996-12-01), None
patent: WO 97/32990 (1997-09-01), None
patent: WO 98/07833 (1998-02-01), None
patent: WO 98/09656 (1998-03-01), None
patent: WO 98/09657 (1998-03-01), None
patent: WO 98/10086 (1998-03-01), None
patent: WO 98/10088 (1998-03-01), None
patent: WO 98/11243 (1998-03-01), None
patent: WO 98/27204 (1998-06-01), None
patent: WO 98/27204 (1998-06-01), None
patent: WO 98/27207 (1998-06-01), None
patent: WO 99/11764 (1999-03-01), None
patent: WO 99/11764 (1999-03-01), None
patent: WO 99/14351 (1999-03-01), None
patent: WO 99/15677 (1999-04-01), None
patent: WO 99/15685 (1999-04-01), None
patent: WO 99/20773 (1999-04-01), None
patent: WO 99/20773 (1999-04-01), None
patent: WO 99/20779 (1999-04-01), None
patent: WO 99/47691 (1999-09-01), None
patent: WO 99/60146 (1999-11-01), None
patent: WO 00/14205 (2000-03-01), None
patent: WO 00/14205 (2000-03-01), None
patent: WO 00/28061 (2000-05-01), None
patent: WO 00/55342 (2000-09-01), None
patent: WO 00/65038 (2000-11-01), None
patent: WO 00/73480 (2000-12-01), None
patent: WO 00/73481 (2000-12-01), None
patent: WO 00/75353 (2000-12-01), None
patent: WO 00/75365 (2000-12-01), None
patent: WO 00/77233 (2000-12-01), None
patent: WO 01/11034 (2001-02-01), None
patent: WO 01/23001 (2001-04-01), None
patent: WO 01/25462 (2001-04-01), None
patent: WO 01/25465 (2001-04-01), None
patent: WO 01/27303 (2001-04-01), None
patent: WO 01/83692 (2001-11-01), None
patent: WO 01/83730 (2001-11-01), None
patent: WO 03/006616 (2003-01-01), None
patent: PCT/US2004/009950 (2004-03-01), None
patent: PCT/US2004/010045 (2004-03-01), None
Aird, W.C. et al. (1995). “Human von Willebrand Factor Gene Sequences Target Expression to a Subpopulation of Endothelial Cells in Transgenic Mice,”PNAS92:4567-4571.
Arnold, T. et al. (1997). “In Vivo Gene Transfer into Rat Arterial Walls with Novel Adeno-Associated Virus Vectors,”J. Vascular Surgery25(2):347-355.
Bonthron, D. et al. (1988). “The Human von Willebrand Factor Gene. Structure of the 5′ Region,”Eur. J. Biochem. 15(171):51-57.
Gnatenko, D. et al. (1994). “Adeno-Associated Virus-2 as a Vehicle for Gene Delivery into Vascular Endothelial Cells,”Blood84(Supp.):741a (Abstract No. 2949).
Gnatenko, D. et al. (1996). “Generation and Characterization of Recombinant Adeno-Associated Viral (rAAV) Vectors for Factor VIII Gene Therapy,”Blood88(Supp.):139a (Abstract No. 543).
Gnatenko, D. et al. (1996). “Recombinant Adeno-Associated Virus-2 (rAAV) as a Vector for Gene Delivery into Vascular Cells,”J. Invest. Med. 44(Supp.):319a (Abstract).
Gnatenko, D. et al. (1997). “Characterization of Recombinant Adeno-Associated Virus-2 as a Vehicle for Gene Delivery and Expression into Vascular Cells,”J. Invest. Med. 45(2):87-98.
Gnatenko, D. et al. (1997). “Recombinant Adeno-Associated Virus as a Vehicle for Gene Delivery of Human Mutant Factor VIII,”Blood90(Supp.):119a (Abstract No. 518).
U.S. Appl. No. 09/561,190, filed Apr. 27, 2000, Lockert et al.
U.S. Appl. No. 09/578,561, filed May 25, 2000, Rasty et al.
U.S. Appl. No. 09/665,852, filed Sep. 20, 2000, Wilson et al.
U.S. Appl. No. 09/684,554, filed Oct. 6, 2000, Engelhardt et al.
U.S. Appl. No. 09/689,136, filed Oct. 12, 2000, Engelhardt et al.
U.S. Appl. No. 09/689,430, filed Oct. 12, 2000, Walsh et al.
U.S. Appl. No. 10/089,394, filed Mar. 29, 2002, Chen et al.
U.S. Appl. No. 10/375,777, filed Feb. 26, 2003, Johnson.
U.S. Appl. No. 10/615,119, filed Jul. 7, 2003, Lynch et al.
U.S. Appl. No. 10/815,262, filed Mar. 31, 2004, Engelhardt et al.
U.S. Appl. No. 10/815,557

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