Transcriptional cofactor DCoH

Details Transcriptional cofactor DCoH Transcriptional cofactor DCoH

1994-11-15

1997-04-15

LeGuyader, John

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

435 691, 4351723, 4353201, 536 231, 536 235, C12N 1585, C12N 1512, C07H 2104

Patent

active

056208871

ABSTRACT:
Methods and compositions are provided for producing and utilizing nucleic acid and peptide sequences associated with cofactors which bind to transcription factors to enhance transcriptional activity of the transcriptional factors and maintain the transcriptional factors as dimers. The compositions can be used for modulating expression of genes, particularly coordinately regulated genes, as evidenced by the combination of the transcription factors HNF-1.alpha. and -1.beta. with the cofactor DCoH.

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