Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Patent
1997-11-24
2000-05-09
Brusca, John S.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
514 44, 536 245, C12N 506, C12N 510, A61K 3170, C07H 2100
Patent
active
060603100
ABSTRACT:
The present invention provides compositions with high affinity for a target transcription factor, that can be introduced into cells as decoy cis-elements to bind the factor and alter gene expression. Specifically, the present invention provides nucleic acid molecules that compete with cAMP response element (CRE) enhancers for binding to transcription factors.
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Brusca John S.
Larson Thomas G.
The United States of America as represented by the Department of
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