Transactivation method of regulating foreign gene expression

Details Transactivation method of regulating foreign gene expression Transactivation method of regulating foreign gene expression

1995-05-16

1999-02-02

LeGuyader, John L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 4353201, 435325, 435 703, C12N 510, C12N 1585, C12P 2100

Patent

active

058663592

ABSTRACT:
The present invention provides a process and host cell for use in increasing the amount of a desired protein produced by a cell line. The process and the cell line use a first transcription unit containing a gene for a transactivator protein to control the transactivation of a second transcription unit such that the amount of desired protein expression can be increased without affecting adversely cell growth. Preferred transactivator proteins are derived from E1A.

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