Trans,trans-2,3,4,5-tetradehydro-PGI.sub.1 , compounds

Details Trans,trans-2,3,4,5-tetradehydro-PGI.sub.1 , compounds Trans,trans-2,3,4,5-tetradehydro-PGI.sub.1 , compounds

1977-08-03

1978-08-22

Jiles, Henry R.

Harness for working animal

542416, 542418, 542421, 542429, 26034622, 26034673, C07D30793

Patent

active

041090829

ABSTRACT:
This invention relates to certain structural and pharmacological analogs of prostacyclin (PGI.sub.2) wherein the C-5 to C-6 double bond is isomerized to the C-4 to C-5 position. These novel trans-4,5-didehydro-5,6-dihydro prostacyclin-type compounds are useful as smooth muscle stimulators.

REFERENCES:
johnson et al., Prostaglandins 12, 915 (1976).

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