Trans-4-aminomethylcyclohexane-1-carboxylic acid

Details Trans-4-aminomethylcyclohexane-1-carboxylic acid Trans-4-aminomethylcyclohexane-1-carboxylic acid

1969-06-04

1976-04-13

Weinberger, Lorraine A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260468J, 424319, C07C 6108

Patent

active

039504050

ABSTRACT:
A trans isomer of 4-cyanoncyclohexane-1-carboxylic acid or its lower alkyl ester is reduced in a solvent in the presence of a hydrogenating catalyst, and hydrolyzing the produced ester in case the starting trans-isomer is a lower alkyl ester, then the trans-4-aminomethyl-cyclohexane-1-carboxylic acid is recovered from the reaction mixture.

REFERENCES:
Meyer, J. Med. Chem., 15, 641 (1966).
Einhorn; A. et al., Justus Liebigs Annalen der Chemie, Vol. 310, pp. 194-204 (1900).

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