Trans-4-(2-chlorophenoxy)-1-ethyl-3-pyrrolidinol and anti-depres

Details Trans-4-(2-chlorophenoxy)-1-ethyl-3-pyrrolidinol and anti-depres Trans-4-(2-chlorophenoxy)-1-ethyl-3-pyrrolidinol and anti-depres

1983-04-22

1984-06-05

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

548541, A61K 3140, C07D20712

Patent

active

044528094

ABSTRACT:
Cis and trans-3-aryloxy-4-hydroxypyrrolidines and derivatives thereof having the formula: ##STR1## are disclosed wherein R.sub.1 is hydrogen, loweralkyl, benzyloxycarbonyl and N-loweralkylcarbamoyl; R.sub.2 is hydrogen, lower alkyl, cycloalkyl, phenylalkyl, benzyloxycarbonyl, carbamoyl, N-loweralkylcarbamoyl, N-diloweralkylcarbamoyl and parafluorobenzoyl-lower-alkyl; Ar is phenyl, substituted phenyl, 1-naphthyl, 2-naphthyl, 1-indenyl and 2-indenyl and pharmaceutically acceptable acid addition and quaternary salts thereof. The compounds have antidepressant, antihypertensive and antiarrythmic activity in animals.

REFERENCES:
patent: 4320137 (1982-03-01), Paoni

Affiliated with

Also associated with

Rating

Trans-4-(2-chlorophenoxy)-1-ethyl-3-pyrrolidinol and anti-depres does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Trans-4-(2-chlorophenoxy)-1-ethyl-3-pyrrolidinol and anti-depres, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Trans-4-(2-chlorophenoxy)-1-ethyl-3-pyrrolidinol and anti-depres will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1497123