Trans-3,4-chroman derivatives useful in the prevention or treatm

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514212, 5142337, 514337, 514375, 514456, 514841, 540484, 544151, 546196, 548237, 548525, 549406, A61K 3140, A61K 3142, A61K 3135, A61K 3155

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active

059943904

ABSTRACT:
The present invention relates to therapeutically active compounds of formula I ##STR1## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.

REFERENCES:
patent: 3340276 (1967-09-01), Carney et al.
patent: 3535344 (1970-10-01), Irmscher et al.
Salman et al., J. Med Chem., vol. 26, pp. 592-595, (1983).
Irmscher et al., Liebigs Ann. Chem., vol. 744, pp. 164-177 (1971).

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