Trans-2-substituted-amido-hexahydrobenzo [A]quinolizines

Details Trans-2-substituted-amido-hexahydrobenzo [A]quinolizines Trans-2-substituted-amido-hexahydrobenzo [A]quinolizines

1980-10-02

1981-12-08

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424258, 546 65, C07D45506

Patent

active

043049133

ABSTRACT:
Disclosed are trans-2-substituted-amido-hexahydrobenzo[a]quinolizines represented by the formula: ##STR1## In the above formula, R.sup.1 and R.sup.2 are independently --H or --OCH.sub.3 or when taken together are ##STR2## R.sup.3 is --H or --CH.sub.3 and R.sup.4 is ##STR3## These compounds, and their pharmacologically acceptable, non-toxic, acid addition salts are useful as anti-hypertensive agents.

REFERENCES:
patent: 3634431 (1972-01-01), Van Dyke
patent: 3635986 (1972-01-01), Van Dyke
patent: 4076820 (1978-02-01), Archibald et al.
Chemical Abstracts, 89: 43086n (1978)[Hadley, M., et al., German Ols 2,748,260, 5/11/78].

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