Tranfected human cells expressing human .alpha.-galactosidase A

Details Tranfected human cells expressing human .alpha.-galactosidase A Tranfected human cells expressing human .alpha.-galactosidase A

1997-09-12

2000-07-04

Railey, II, Johnny F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435208, 4353201, 435366, 435367, 435368, 435369, 435370, 435371, 435372, 4353721, 4353722, 4353723, 435455, 536 232, 536 234, C12N 510, C12N 508, C12N 940, C12P 2102

Patent

active

06083725&

ABSTRACT:
A therepeutic method whereby an individual suspected of having an .alpha.-galactosidase A deficiency, such as Fabry disease, is treated either with (1) human cells that have been genetically modified to overexpress and secrete human .alpha.-gal A, or (2) purified human .alpha.-gal A obtained from cultured, genetically modified human cells.

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