Trandermal delivery of opioids

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3144

Patent

active

046265392

ABSTRACT:
Opioid-containing pharmaceutical compositions are provided which are useful in effecting transdermal delivery of a therapeutic dose of the opioid to the systemic circulation of a mammal. These pharmaceutical compositions consist essentially of the opioid, a penetration enhancer which is at least one of a saturated fatty alcohol or fatty acid of 8-15 carbon atoms or of an unsaturated fatty alcohol or fatty acid of 8-18 carbon atoms, and a suitable pharmaceutical carrier, preferably propylene glycol.

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patent: 4416886 (1983-11-01), Bernstein
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