TRAF inhibitors

Details TRAF inhibitors TRAF inhibitors

1998-02-09

2000-05-09

Scheiner, Laurie

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 536 231, 536 235, C12N 120, C07H 2104

Patent

active

060603038

ABSTRACT:
The invention concerns novel inhibitors of tumor necrosis factor receptor associated factor-(TRAF) mediated signal transduction. The invention encompasses the novel inhibitor proteins (I-TRAFs), nucleic acid encoding them, methods for their recombinant production, and their use in screening assays and as pharmaceuticals.

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