Tracer for circulation determinations

Details Tracer for circulation determinations Tracer for circulation determinations

1983-05-27

1985-03-19

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 521 25, 523201, A61K 4300, A61K 4900

Patent

active

045058881

ABSTRACT:
An improved tracer particle is described comprising an ion exchange core having a polymer coating thereon, the coated ion exchange core having a reaction site capable of reacting with a compound containing an oxirane group, said coated ion exchange core having been treated with a compound containing an oxirane group to react with said coated ion exchange core causing an increase in mass of the tracer particle. Preferably, the ion exchange core is labelled with a radionuclide. These particles have improved characteristics including improved stability against leaching and improved handling properties. Such particles are useful in circulatory determinations involving the injection of the particles as a suspension in a physiologically acceptable carrier or medium into the circulatory system of animals.

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