Trace-labeled conjugates of metallothionein and target-seeking b

Details Trace-labeled conjugates of metallothionein and target-seeking b Trace-labeled conjugates of metallothionein and target-seeking b

1983-10-06

1988-03-22

Warden, Robert J.

Chemistry: analytical and immunological testing

Involving production or treatment of antibody

436548, 436804, 436173, 424 11, 424 9, 424 85, 128653, 128654, 530400, 530402, G01N 3353, A61K 4300, C07K 700

Patent

active

047328649

ABSTRACT:
Conjugates of target-seeking biologically active molecules and metallothionein in which all or part of the metal in the metallothionein is suitable for diagnostic or therapeutic applications.

REFERENCES:
patent: 4472509 (1984-09-01), Gansow et al.
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Robert C. Brasch, M.D., Radiology, 147: 781-788, (1983).
Metallothioneins, pp. 46-92, Jul. 17-22, 1978, Kagi and Noldberg.
Rupp and Weser, Biochimica et Biophysica Acta, 533, p. 209, (1978), Disclosing Zn, Cd, and Hg Metallothionein.
Yoshida et al., Proc. Natl. Acad. Sci., U.S.A., 76, p. 486, (1970), Disclosing Zn, Cd, and Hg Metallothionein.
Webb and Cain, Biochemical Pharmacology, 31, p. 137, (1982), Disclosing Cd, Zn and Cu Metallothionein.
Nordberg and Nordberg, Environmental Health Perspectives, 12, p. 103, (1975).
Vander Mallie and Garvey, Immunochemistry, 15, p. 857, (1978).
Kagi and Vallee, J. Biol. Chem., 236, p. 2435, (1961), Disclosing CD and Zn Metallothionein.

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