Trace amine receptor 1 of the African green monkey

Details Trace amine receptor 1 of the African green monkey Trace amine receptor 1 of the African green monkey

2008-05-06

2008-05-06

Ulm, John (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S069100, C536S023500

Reexamination Certificate

active

07368541

ABSTRACT:
A trace amine receptor 1 has been isolated from the genome ofCercopithecus aethiops(African green monkey). Described is the amino acid sequence of the receptor, the nucleic acid encoding the receptor, and methods for using the receptor to identify analytes that are agonists or antagonists of the receptor.

REFERENCES:
patent: 6783973 (2004-08-01), Bunzow et al.
patent: WO 00/73449 (2000-12-01), None
patent: WO 01/72841 (2001-10-01), None
patent: WO 02/22801 (2002-03-01), None
Borowsky, et al., “Trace amines: Identification of a family of mammalian G protein-coupled receptors”, PNAS, Jun. 31, 2001, vol. 98, No. 16, pp. 8966-8971.
Branchek, et al., “Trace amine receptors as targets for novel therapeutics: legend, myth and fact”, Current Opinion in Pharmacology, vol. 3, pp. 90-97, 2003.
Bunzow, et al., “Amphetamine, 3,4-Methylenedioxymethamphetamine, Lysergic Acid Diethylamide, and Metabolites of the Catecholamine Neurotransmitters Are Agonists of a Rat Trace Amine Receptor,” Molecular Pharmacology, vol. 60, No. 6, pp. 1181-1188, 2001.
D'Andrea, et al., Elevated levels of circulating trace amines in primary headaches, Neurology, vol. 62, May 2004, pp. 1701-1705.
GenBank AY135366, May 18, 2005.
GenBank NM—053205, Apr. 16, 2005.
GenBank NM—134328, Oct. 17, 2005.
GenBank NM—138327, Oct. 21, 2005.
Kim, et al., “Old Drugs Learn New Tricks: Insights from Mammalian Trace Amine Receptors”, Molecular Pharmacology, vol. 60, No. 6, p. 1165-1167, 2001.
Miller, et al., “Cloning of Rhesus Monkey TAR-1, A Novel G-Protein-Linked Receptor for “Trace” Amines”, Program 10.1, 2002 Abstract Viewer/Itinerary Planner, Washington, DC: Society for Neuroscience, 2002.

Affiliated with

Also associated with

Rating

Trace amine receptor 1 of the African green monkey does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Trace amine receptor 1 of the African green monkey, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Trace amine receptor 1 of the African green monkey will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2802818