TPR-containing genes

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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4353201, 4352523, 530350, 536 235, C12N 1512, C12N 121, C12N 510, C07K 14435

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active

059358513

ABSTRACT:
The present invention relates, in general, to novel TPR-containing genes, tpr1 and tpr2. In particular, the present invention relates to nucleic acid molecules coding for tpr1 and tpr2; purified tpr1 and tpr2 polypeptides; recombinant nucleic acid molecules; cells containing the recombinant nucleic acid molecules; antibodies having binding affinity specifically to tpr1 and tpr2 polypeptides; hybridomas containing the antibodies; nucleic acid probes for the detection of tpr1 and tpr2; a method of detecting the novel tpr1 and tpr2 nucleic acids or polypeptides in a sample; and kits containing nucleic acid probes or antibodies. Therapeutic uses for the tpr1 and tpr2 polypeptides are also provided.

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