Toxoplasma gondii P28 gene and methods for its use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 435 71, 435 72, 536 231, 536 243, 536 2432, C12Q 168, C12P 1934, C07H 2102, C07H 2104

Patent

active

056331398

ABSTRACT:
Genetic material encoding the P28 peptide of Toxoplasma gondii has been isolated and characterized. This genetic material allows the production of peptides for use in diagnosis or immunization or can itself be directly used in hybridization assays.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
Handeman and J.S. Remington, Immunology 40:579-587 1980.
Handman and Remington, "Serological and Immunochemical Characterization of Monoclonal Antibodies to Toxoplasma gondii", Immunology, 40:579-588 (1980).
Remington et al., "A Role for Activated Macrophages in Resistance to Infection with Toxoplasma", Infection and immunity, 6(5):829-834 (1992).
Sharma et al., "Toxoplasma Antigen Isolated by Affinity Chromatography with Monoclonal Antibody Protects Mice Against Lethal Infection with Toxoplasma gondii", J. of Immunology, 133(6):2818-2820 (1984).

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