Toxoplasma gondii antigens

Details Toxoplasma gondii antigens Toxoplasma gondii antigens

1995-10-06

1999-02-23

Hutzell, Paula J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

530350, 530325, 530330, 5303871, 530403, 530822, 4241841, 4241301, 4242691, 435 722, 435975, C07K 1445, C07K 700, C07K 1400, A61K 3902

Patent

active

058745262

ABSTRACT:
The present invention relates to peptides immunoreactive with antibodies to Toxoplasma gondii, nucleic acid sequences encoding these peptides, recombinant vector molecules, comprising these nucleic acid sequences, host cells transformed with the recombinant vector molecule, immunochemical reagents comprising the peptides or antibodies directed against the peptides, a test kit for the detection of T. gondii infections as well as a vaccine for the protection against T. gondii infections.
In particular the present invention provides peptides comprising part of the amino acid sequence as shown in SEQ ID No.: 1.
A preferred embodiment of the present invention are peptides comprising at least part of the amino acid sequence shown in SEQ ID No.: 3 or 5.
It has been found that the peptides according to the present invention are particularly suitable for diagnosing T. gondii infected humans.

REFERENCES:
patent: 4879213 (1989-11-01), Fox et al.
L. Lecordier et al., Mol. Biochem. Parasitol., 59:1:143-154, 1993.
H. Charif et al., Exp. Parasitol., 71:1:114-124, 1990.

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