Tourette syndrom, autism and associated behaviors

Details Tourette syndrom, autism and associated behaviors Tourette syndrom, autism and associated behaviors

1990-08-03

1995-04-11

Fleisher, Mindy B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 935 77, 935 78, C07H 2102, C07H 2104, C12Q 168, C12N 1500

Patent

active

054059437

ABSTRACT:
The human tryptophan oxygenase gene sequence and chromosomal location are described. Procedures for the diagnosis of genetic Tourette syndrome and many psychiatric and behavioral disorders by genetic tests to identify deletions or defective alleles in the human tryptophan oxygenase (TO) gene and cDNA probes for use in such tests are also described.

REFERENCES:
Fritsch et al., Cell, vol. 19, Apr. 1980 pp. 959-972.
Mangoni, Adv. in Biochem. Psychoprarm. vol. 11, 1974, pp. 293-298.
White et al, Principles of Biochemistry, McGraw-Hill, p. 750.
Matsubara et al, Proc. Natl. Acad. Sci, vol. 83, Sep. 1986, pp. 6543-6547.
Schmid et al, EMBO J, vol. 1, No. 10, 1982, pp. 1287-1293.

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