Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-12-05
1996-06-18
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549448, 549510, 549511, C07D33908, C07D30514, C07D31712
Patent
active
055279244
ABSTRACT:
The present invention provides two basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogs to taxol. Both the intermediates and analogs to taxol may prove to be valuable anticancer agents.
REFERENCES:
patent: 5416225 (1995-05-01), Danishefsky et al.
Bornmann William G.
Danishefsky Samuel J.
Krol Walter J.
Magee Thomas V.
Queneau Yves
Ivy C. Warren
Sloan-Kettering Institute for Cancer Research
Trinh Ba K.
White John P.
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