Total synthesis of steganacin and derivatives thereof

Details Total synthesis of steganacin and derivatives thereof Total synthesis of steganacin and derivatives thereof

1975-12-22

1977-01-18

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D31744

Patent

active

040039161

ABSTRACT:
Steganacin and Steganangin, dibenzocyclooctadiene lignan lactones, have been reported to possess antileukemic activity. This invention describes the first total synthesis of these compounds and other relevant intermediates.

REFERENCES:
kupchan et al., Journ. Amer. Chem. Soc., 95(4), 1335.
Kende et al., Journ. Amer. Chem. Soc., 98(1), pp. 267-268 (1976).
Becker et al., Journ. Chem. Soc., Chem Commun. p. 431 (1974).

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