Total synthesis of (.+-.)-picropodophyllone and (.+-.)-4'-demeth

Details Total synthesis of (.+-.)-picropodophyllone and (.+-.)-4'-demeth Total synthesis of (.+-.)-picropodophyllone and (.+-.)-4'-demeth

1977-08-25

1978-10-24

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239A, 2603433R, C07D31744

Patent

active

041220927

ABSTRACT:
Efficient total syntheses of (.+-.)-picropodophyllone and (.+-.)-4'-demethylpicropodophyllone are described. These compounds are intermediates in the preparation of known antineoplastic agents.

REFERENCES:
patent: 4059593 (1977-11-01), Kende et al.
Gensler et al., Journ. Amer. Chem. Soc. 82, pp. 1714-1727 (1960).

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