Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B

Details Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B

1982-11-10

1984-01-24

Bond, Robert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D48704

Patent

active

044275870

ABSTRACT:
A new chemical synthesis of the pyrrolobenzodiazepine antibiotics BBM-2040A and B is disclosed. The disclosed total synthesis uses readily available starting materials and provides a useful alternative to the microbiological procedure previously used to prepare these antibiotics.

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