Total or partial esters of hyaluronic acid

Details Total or partial esters of hyaluronic acid Total or partial esters of hyaluronic acid

1992-12-30

1994-08-09

Page, Thurman K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424443, C07H 504

Patent

active

053367677

ABSTRACT:
The invention concerns the esters of hyaluronic acid in which all or only a portion of the carboxylic groups of the acid are esterified, and the salts of the partial esters with metals or with pharmacologically acceptable organic bases. The compounds possess interesting and precious bioplastic and pharmaceutical properties and may be used in innumerable fields, including cosmetics, surgery and medicine. The invention also includes pharmaceutical preparations containing, as an active ingredient, one or more hyaluronic acid esters, or a salt thereof as described above, as well as medicaments containing:
1) a pharmacologically active substance or an association of pharmacologically active substances and
2) a carrying vehicle containing a total or partial ester of hyaluronic acid. The invention includes also various uses of the hyaluronic esters or of the above mentioned medicaments, such as in medicine, surgery or cosmetics. The invention relates to a new procedure for the preparation of polysaccharide esters containing carboxylic groups, such as in particular the above mentioned hayluronic acid esters

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