Total mitral heterologous bioprosthesis to be used in mitral or

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Heart valve – Having rigid or semirigid pivoting occluder

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623900, A61F 224

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057333319

ABSTRACT:
The present invention relates to a heterologous total stentless mitral valve prosthesis for the use in mitral and tricuspid position which provides for better hemodynamic performance. This mitral valve prosthesis addresses the specific needs of flow and contractility, thereby prolonging durability. The heterologous total stentless mitral heart valve prosthesis of this present invention comprises one sewing ring, leaflets, and subvalvular apparatus having new chordal insertions which are fixed to or in between two heterologous pericardial patches. This heart valve prosthesis is obtained from heterologous mammals, such as swine, ovine, bovine, and moreover, the pericardial patches used may also be of synthetic material. The heart valve prosthesis presents specific design benefits from its anatomical and functional characteristics permitting chordal insertion to the papillary muscles and attachment of its sewing rim to the mitral annulus of the recipient, thereby providing for better hemodynamic performance and avoiding disfunction and dilatation of the left ventricle.

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Herbert Vetter, et al., New Horizons and the Future of Heart Valve Bioprostheses, First Edition, 1994, pp. 93-104.
Mario Osvaldo Vrandecic Peredo et al., Anatomically Complete Heterograft Mitral Valve Substitute: Surgical Technique and Immediate Results, The Journal of Heart Valve Disease.1991: 1:254-259.
Mario Osvaldo Vradecid Peredo et al., Heterologous Mitral Valve Transplant, New Alternative For Mitral Replacement: One Year Clinical Follow-Up, Heart Surgery 1993, Ed. Luigi C. D'Alessandro., Casa Editrice Scientifica Internazionale, Chapter 7, pp. 57-68.
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