Topoisomerase I selective cytotoxic sugar derivatives of...

Details Topoisomerase I selective cytotoxic sugar derivatives of... Topoisomerase I selective cytotoxic sugar derivatives of...

2005-02-15

2005-02-15

Lewis, Patrick T. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S042000, C514S410000, C536S018700, C536S022100, C536S027100, C536S028600

Reexamination Certificate

active

06855698

ABSTRACT:
The present invention relates to fluoro sugar and other sugar derivatives of indolopyrrolocarbazoles, their salts and hydrates, which exhibit selective topoisomerase I (topo I) activity, are useful in inhibiting the proliferation of tumor cells and exhibit an antitumor effect, as well as processes for their preparation.

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