Topiramate immunoassay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 75, 435188, 436537, 436545, 436546, 436815, 5303889, 5303898, 530404, G01N 33533, G01N 33535, C07K 1644, C12N 996

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active

059521872

ABSTRACT:
The present invention provides a topiramate immunoassay and reagents for use in the immunoassay. In particular, topiramate is derivatized at the sulfamate moiety or the 9-carbon or 10-carbon methyl group of topiramate to add a label bound directly or through a linking group for use as a tracer (competitive analyte analog) or to add a linking group bound to a carrier for use as an immunogen to induce anti-topiramate antibodies. Immunoassay methods and kits are also provided.

REFERENCES:
patent: 4492762 (1985-01-01), Wang et al.
patent: 4668640 (1987-05-01), Wang et al.
patent: 4751190 (1988-06-01), Chiapetta et al.
patent: 5051361 (1991-09-01), Stenglein et al.
J. Burrin et al., Principles and Practice of Immunology, (Price, C.P. and Newman, D. Hrsg.), Stockton Press, NY, pp. 19-52 (1992).
Doose et al., "Comparison of a Fluorescence Polarization Immunoassay with a Capillary GCNPD Assay for the Antiepileptic Agent, Topiramate in Human Plasma," Epilepsia, 36, (1995) Supplement 4, p. 48.
Holland et al., "Automated Capillary Gas Chromatographic Assay Using Flame Ionization Detection for the Determination of Topiramate in Plasma," Journal of Chromatography, 433 (1988), pp. 276-281.
Maryanoff et al., "Anticonvulsant .omicron.-Alkyl Sulfamates. 2,3:4,5-Bis-.omicron.-(1-methylethylidene)-.beta.-D-fructopyranose Sulfamate and Related Compounds," J. Med. Cem. 30, (1987), pp. 880-887.

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