Topical transdermal treatments

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...

Reexamination Certificate

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Reexamination Certificate

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06858232

ABSTRACT:
Jojoba alcohol, a mixture of long chain monounsaturated alcohols, is an oily liquid at moderate ambient temperatures. It is readily absorbed by human skin where it relieves irritation and inhibits the formation of lesions caused by viruses. The inhibitory action is applicable to enveloped viruses such as herpes simplex, which express as sores at dermal surfaces in humans. When applied topically to an incipent herpes episode, it will quickly penetrate the epidermis to the subdermal vascular cells and suppress viral replication which leads to inflammation and the formation of blisters on the face, genital and other skin and mucosal areas. Compositions of certain low molecular weight organic acids in jojoba alcohol enhance antiviral activity. Jojoba alcohol is a carrier and transdermal delivery system for these and other pharmacologically active agents for the relief of pain and treatment of other conditions which occur at or under the surface of the skin. Topically applied jojoba alcohol is non-toxic and safe for animals and humans.

REFERENCES:
patent: 5750563 (1998-05-01), Honda
patent: 5760096 (1998-06-01), Thornfeldt et al.
patent: 5945409 (1999-08-01), Crandall
patent: 5968530 (1999-10-01), Arquette
patent: 267617 (1988-05-01), None
patent: 111903 (1958-05-01), None
Yukawa et al., Yakuzaigaku, 1989, 49(3), 254-62.

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