Topical skin protectants

Details Topical skin protectants Topical skin protectants

1995-05-30

1997-03-04

Dodson, Shelley A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Halogenated hydrocarbon doai

514723, 514772, 514789, 514844, 514937, 514939, 514944, 514947, 514845, 514846, 514847, 514873, A61K 3102, A61K 3108

Patent

active

056079796

ABSTRACT:
Creams formed from about 35% to about 50% fine particulates of certain poly(tetrafluoroethylene) (PTFE) resins dispersed in perfluorinated polyether oils having viscosities from about 20 cSt to about 350 cSt afford good protection against chemical warfare agents such as sulfur mustard (HD), lewisite (L), sulfur mustard/Lewisite mixtures (HL), pinacolyl methylphosphonofluoridate (soman or GD), thickened soman (TGD) and O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (vx).

REFERENCES:
patent: 4751075 (1988-06-01), Chernowsky et al.
patent: 4803067 (1989-02-01), Drunetta et al.
patent: 5019604 (1991-05-01), Lemole
McCreery et al, "Formulation Optimization for Perflroronated Topical Skin otectants" Abstract U.S. Army Medical Research and Development Command 1993 Medical Defense Bioscience Review Proceedings May 10-13, 1993 Proceedings, vol. 1, pp. 293-294.
Snider et al. "An in vitro Cultured Skin Penetration" . . . Abstract #341, 1994 Annual Meeting of the Society of Toxicology plus text of poster.

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