Topical siloxane sunscreen compositions having enhanced performa

Details Topical siloxane sunscreen compositions having enhanced performa Topical siloxane sunscreen compositions having enhanced performa

1991-03-27

1997-11-11

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Topical sun or radiation screening, or tanning preparations

424 60, 514569, A61K 742, A61K 744

Patent

active

056860650

ABSTRACT:
Methods and compositions that provide for the long-term adhesion and slow-release of various bioactive agents on the surface of human skin utilize siloxane bridging agents activated for reaction with the skin surface which bind the bioactive agent to the skin surface. Since the topical agent remains bound to the continuously renewing epidermis, safety is enhanced for many bioactive agents. Slight modifications of the siloxane bridging compounds or bioactive agents allows for more or less adhesion to the skin, controlling the degree of release of the agent. Skin treatments according to the invention can provide enhanced repellency to microorganisms, insect bites, sun, water, poison ivy/oak, and other skin irritants, and other effects such as artificial skin coloring and administration of topical drugs, among others.

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