Topical prophylaxis against schistosomiasis

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 31135

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042822530

ABSTRACT:
An improved method is provided for the prevention of schistosomiasis in her animals. The topical application of a composition containing a dehydroabietylamine or a derivative thereof provides a coating of perdurable anti-penetrant through which the infective cercariae of the parasitic worm do not pass readily.

REFERENCES:
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Pellegrino-Experimental Parasitology, vol. 21 (1967), pp. 112-131.
Austin et al., Amer. J. Trop. Med. Hyg., vol. 22 (1973), pp. 743-747.
Gilbert et al., J. Parasitology, vol. 56 (1970), pp. 397-398.
Hunter et al., Amer. J. Trop. Med. Hyg. vol. 5 (1956) pp. 713-736.
Nolan et al., Amer. J. Trop. Med. Hyg., vol. 4 (1955), pp. 152-155.
Mueller-Chem. Abst. vol. 64 (1966), p. 4844g.
Gottstein et al., J. Org. Chem., vol. 30 (1965), pp. 2072-2073.

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