Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Patent
1996-06-20
1998-09-08
Gardner-Lane, Sally
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
424617, 4241951, 514847, 514859, 514887, A61K 748, A61K 3324
Patent
active
058042032
ABSTRACT:
Topical formulations comprising an anti-irritant amount of aqueous-soluble strontium (Sr.sup.2+) cation, and method for using the same to inhibit skin irritation are disclosed.
REFERENCES:
patent: 3716054 (1973-02-01), Porter et al.
patent: 4105782 (1978-08-01), Yu et al.
patent: 4105783 (1978-08-01), Yu et al.
patent: 4191750 (1980-03-01), Hodosh
patent: 4285973 (1981-08-01), Edwards
patent: 4388301 (1983-06-01), Klein
patent: 4477439 (1984-10-01), D'alelio
patent: 4943432 (1990-07-01), Biener
patent: 4971800 (1990-11-01), Chess et al.
patent: 5262153 (1993-11-01), Mishima et al.
Bilotto, Gerardo, et al., "Effects of Ionic and Non-Ionic Solutions on Intradental Nerve Activity in the Cat," Pain, 32:231-238, 1988.
Celerier, et al., "Modulatory Effects of Selenium and Strontium Salts on Keratinocyte-Derived Inflammatory Cytokines," Arch. Dermatol. Res., vol. 287, pp. 680-682 (1985).
Foreman, J.C. et al., "Movement of Strontium Ions into Mast Cells and its Relationship to the Secretory Response", J. Physiol., 271:233-251, 1977.
Frankenhaeuser, Bernhard, et al., "The Effect of Magnesium and Calcium on the Frog Myelinated Nerve Fibre," J. Physiol., 142:360-365, 1958.
Gutentag, Herb, "The Effect of Strontium Chloride on Peripheral Nerve in Comparison to the Action of `Stabilizer` and `Labilizer` Compounds," Penn Dental Journal, 68(2):37-43, Feb. 1965.
Kato, G., et al., "Anaesthetic Action of Magnesium Ions," Can. Anaes. Soc. J., 15(6):539-544, Nov. 1968.
Kim, Syngcuk, "Hypersensitive Teeth: Desensitization of Pulpal Sensory Nerves," J. Endodontics, 12(10):482-485, Oct. 1986.
Markowitz, K., et al., "Decreasing Intradental Nerve Activity in the Cat with Potassium and Divalent Cations," Archs. Oral Biol., 36(1):1-7, 1991.
Markowitz, K., et al., "The Role of Selected Cations in the Desensitization of Intradental Nerves," Proc. Finn. Dent. Soc., 88 (Suppl I):39-54, 1992.
Orchardson, R., "Is Calcium More Effective than Strontium as a Desensitizing Agent for Dentine?," in Lesney & Matthew (eds.), Current Topics in Oral Biology, Univ. of Bristol Press (Bristol, 1985), pp. 205-215.
Penny, Deborah, et al., "Fast Desensitization of Tooth Roots by Topically Applied SnF.sub.2 and SrCl.sub.2 in Dogs," Archs. Oral Biol., 21(6):339-347, 1976.
Shioya, Takao, et al., "Fast and Slow Blockades of the Inward-Rectifier K.sup.30 Channel by External Divalent Cations in Guinea-Pig Cardiac Myocytes," Pflugers Arch., 422:427-435, 1993.
Sohn et al, "Agonist-Independent, Muscle-Type-Specific Signal Transduction Pathways in Cat Esophageal and Lower Esophageal Sphincter Circular Smooth Muscle," J. Pharmacol. & Exp. Therap., vol. 273, No. 1, pp. 482-491 (1995).
Sohn et al, "Different Receptors Activate a Different Single G-Protein in Esophageal (G.sub.i3) and in LES (G.sub.q) Circular Smooth Muscle," Gastroenterology, vol. 104, abstract p. A585 (Apr. 1993).
Hahn Gary S.
Quick Timothy W.
Thueson David O.
Cosmederm Technologies
Gardner-Lane Sally
LandOfFree
Topical product formulations containing strontium for reducing s does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Topical product formulations containing strontium for reducing s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Topical product formulations containing strontium for reducing s will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1279687