Topical product formulations containing strontium for reducing s

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424617, 4241951, 514847, 514859, 514887, A61K 748, A61K 3324

Patent

active

058042032

ABSTRACT:
Topical formulations comprising an anti-irritant amount of aqueous-soluble strontium (Sr.sup.2+) cation, and method for using the same to inhibit skin irritation are disclosed.

REFERENCES:
patent: 3716054 (1973-02-01), Porter et al.
patent: 4105782 (1978-08-01), Yu et al.
patent: 4105783 (1978-08-01), Yu et al.
patent: 4191750 (1980-03-01), Hodosh
patent: 4285973 (1981-08-01), Edwards
patent: 4388301 (1983-06-01), Klein
patent: 4477439 (1984-10-01), D'alelio
patent: 4943432 (1990-07-01), Biener
patent: 4971800 (1990-11-01), Chess et al.
patent: 5262153 (1993-11-01), Mishima et al.
Bilotto, Gerardo, et al., "Effects of Ionic and Non-Ionic Solutions on Intradental Nerve Activity in the Cat," Pain, 32:231-238, 1988.
Celerier, et al., "Modulatory Effects of Selenium and Strontium Salts on Keratinocyte-Derived Inflammatory Cytokines," Arch. Dermatol. Res., vol. 287, pp. 680-682 (1985).
Foreman, J.C. et al., "Movement of Strontium Ions into Mast Cells and its Relationship to the Secretory Response", J. Physiol., 271:233-251, 1977.
Frankenhaeuser, Bernhard, et al., "The Effect of Magnesium and Calcium on the Frog Myelinated Nerve Fibre," J. Physiol., 142:360-365, 1958.
Gutentag, Herb, "The Effect of Strontium Chloride on Peripheral Nerve in Comparison to the Action of `Stabilizer` and `Labilizer` Compounds," Penn Dental Journal, 68(2):37-43, Feb. 1965.
Kato, G., et al., "Anaesthetic Action of Magnesium Ions," Can. Anaes. Soc. J., 15(6):539-544, Nov. 1968.
Kim, Syngcuk, "Hypersensitive Teeth: Desensitization of Pulpal Sensory Nerves," J. Endodontics, 12(10):482-485, Oct. 1986.
Markowitz, K., et al., "Decreasing Intradental Nerve Activity in the Cat with Potassium and Divalent Cations," Archs. Oral Biol., 36(1):1-7, 1991.
Markowitz, K., et al., "The Role of Selected Cations in the Desensitization of Intradental Nerves," Proc. Finn. Dent. Soc., 88 (Suppl I):39-54, 1992.
Orchardson, R., "Is Calcium More Effective than Strontium as a Desensitizing Agent for Dentine?," in Lesney & Matthew (eds.), Current Topics in Oral Biology, Univ. of Bristol Press (Bristol, 1985), pp. 205-215.
Penny, Deborah, et al., "Fast Desensitization of Tooth Roots by Topically Applied SnF.sub.2 and SrCl.sub.2 in Dogs," Archs. Oral Biol., 21(6):339-347, 1976.
Shioya, Takao, et al., "Fast and Slow Blockades of the Inward-Rectifier K.sup.30 Channel by External Divalent Cations in Guinea-Pig Cardiac Myocytes," Pflugers Arch., 422:427-435, 1993.
Sohn et al, "Agonist-Independent, Muscle-Type-Specific Signal Transduction Pathways in Cat Esophageal and Lower Esophageal Sphincter Circular Smooth Muscle," J. Pharmacol. & Exp. Therap., vol. 273, No. 1, pp. 482-491 (1995).
Sohn et al, "Different Receptors Activate a Different Single G-Protein in Esophageal (G.sub.i3) and in LES (G.sub.q) Circular Smooth Muscle," Gastroenterology, vol. 104, abstract p. A585 (Apr. 1993).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Topical product formulations containing strontium for reducing s does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Topical product formulations containing strontium for reducing s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Topical product formulations containing strontium for reducing s will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1279687

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.