Topical powder compositions containing a cyclic AMP derivative

Details Topical powder compositions containing a cyclic AMP derivative Topical powder compositions containing a cyclic AMP derivative

1994-07-18

1995-06-13

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 2613, A61K 3170, C07H 19213

Patent

active

054242983

ABSTRACT:
A topical powder composition containing a cyclic AMP derivative and a water-absorptive powdery material. The topical powder composition is useful for wet dermatoses. Release of drug can be controlled.

REFERENCES:
patent: 3849553 (1974-11-01), Dea et al.
patent: 3860706 (1975-01-01), Ikeda et al.
patent: 4369181 (1983-01-01), Miller et al.
patent: 4873227 (1989-10-01), Ikada et al.
"Polyoxyethylene Alcohols," Merck Index, Merck & Co., Rahway, N.J., 1983, p. 1094, Entry 7449, p. 1094.
"Poly(ethylene glycol)," Aldrich Catalog/Handbook of Fine Chemicals, Aldrich Chemical Co., Milwaukee, Wis., 1984, see pp. 906-907; see also as Exhibit A in applicants submission of Jan. 21, 1994.
Mafune et al., "Effect of Vehicles on Percutaneous Absorption of Dibutyryl Cyclic AMP (DBcAMP) in the Rat Skin," Proc. Intern. Symp. Control Rel. Bioact. Mater., 18, 517-518 (1991); Abstract #580, supplied by applicant attached to Takasugi declaration of Mar. 18, 1993 (Exhibit E).
Encyclopedia Chimica, vol. 8, p. 743 (1960).
Translation of Table in Encyclopedia Chimica, p. 743.
U.S. Pharmacopia, vol. 22 (XXII), Published Jul. 1989, 1990 Edition.

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