Topical patch for liposomal drug delivery system

Details Topical patch for liposomal drug delivery system Topical patch for liposomal drug delivery system

1994-11-21

1998-02-17

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424449, 604307, A61K 9127

Patent

active

057189145

ABSTRACT:
A device for the dermal and transdermal delivery of liposomes or a formulation thereof. The device comprises an applicator element carrying a containment means to store the liposomes, a liposome delivery surface for the containment means to transfer the liposomes from storage to the skin when the surface is brought into operating proximity therewith and a detachable cover means for the surface. Preferably, the device comprises a screen covering the containment means. The screen is characterized in that it is sufficiently hydrophobic to constitute a barrier for preventing passage of the liposomes when the screen is not in contact with the skin. It also has a plurality of pores of sufficient diameter to allow passage of the liposomes through the screen when the screen is in contact with the skin.

REFERENCES:
patent: 4849224 (1989-07-01), Chang
patent: 4904475 (1990-02-01), Gale
patent: 4921757 (1990-05-01), Wheatley

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