Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation
Patent
1990-07-06
1993-02-23
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Ophthalmic preparation
424427, 424428, 424484, 424486, 424487, 5147723, 5147724, 5147726, 514912, 514913, 514914, 514944, 514953, 514954, 514955, A61K 908, A01N 2502
Patent
active
051888262
ABSTRACT:
A topical, aqueous ophthalmic gel suspension for dry eye is administrable to the eye in drop form, remains as a gel in the eye for a prolonged time, and releases water and one or more ophthalmic demulcents or vasoconstrictors. It comprises water and from 0.1% to 6.5% by weight of lightly cross-linked carboxyl-containing polymer having a particle size of not more than about 50 .mu.m in equivalent spherical diameter. The suspension is at a pH of from 6.6 to 8.0, has an osmolality of from 50 to 400 mOsM, and a viscosity of from about 500 to about 4,000 centipoise (0.5 to 4 Pa.s).
REFERENCES:
patent: 3947573 (1976-03-01), Rankin
patent: 4271143 (1981-06-01), Schoenwald et al.
patent: 4407792 (1983-10-01), Schoenwald et al.
patent: 4474751 (1984-10-01), Haslam et al.
patent: 4478818 (1984-10-01), Shell et al.
patent: 4615697 (1986-10-01), Robinson
patent: 4820737 (1989-04-01), Schoenwald et al.
patent: 4911920 (1990-03-01), Jani et al.
Canadian Journal of Pharmaceutical Science, vol. 10, No. 1, pp. 16 et seq. (1975).
Pharmaceutica Acta Helvetiae, vol. 39, pp. 615 et seq. (1964).
Ophthalmology, 91, No. 10 (Oct. 1984), pp. 1199-1204 (Liebowitz et al.)
Klin. Mbl. Augenheilk., 189 (1986), at pp. 51-54 and pp. 254-257 (Marguardt et al.).
Pharmaceutica Acta Helvetiae, vol. 39, pp. 546 et seq. (1964).
Archibald Roy D.
Babcock John C.
Bowman Lyle M.
Chandrasekaran Santosh K.
Reents Margaret J.
Azpuru Carlos
InSite Vision Incorporated
Page Thurman K.
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