Topical ophthalmic pharmaceutical vehicles

Details Topical ophthalmic pharmaceutical vehicles Topical ophthalmic pharmaceutical vehicles

1994-01-07

1995-10-24

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Solid synthetic organic polymer

514 54, 514781, 514782, 514912, A61K 4700, A61K 31715

Patent

active

054610818

ABSTRACT:
Universal ophthalmic pharmaceutical vehicles which increase in viscosity upon instillation in the eye are disclosed. Ophthalmic compositions of the universal vehicle and a pharmaceutically active drug are also disclosed. In one embodiment, the vehicle gels upon instillation in the eye. In another embodiment, suspension vehicles having superior physical stability are provided.

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Saettone et al., "Vehicle effects on ophthalmic bioavailability: the influence of different polymers on the activity of pilocarpine in rabbit and man," J. Pharm. Pharmacol., vol. 34 pp. 464-466 (1982).
B. F. Goodrich Carbopol.RTM. Resins-Product Information (1991).

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