Topical ophthalmic analgesic preparations for sustained and exte

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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514563, 514912, A61K 3124

Patent

active

057600775

ABSTRACT:
A preparation suitable for sustained and extended corneal analgesia and for repeated administration consisting of ultralow nontoxic subanaesthetic concentrations of local anesthetic agents. A method for corneal analgesia has a fast onset of pain relief and extended duration of the corneal analgesia for several months without accompanying toxic symptoms by administering to a patient an ophthalmic analgesic solution containing a local anesthetic agent in subanesthetic concentration.

REFERENCES:
Steve Arshinoff, M.D., Use of Topical Nonsteroidal Anti-inflammatory Drugs in Excimer Laser Photorefractive Keratectomy, J Cataract Refract Sur, vol. 20, 216-222, (Supplement 1994).
Jean Daniel Arbour, M.D., et al, Should We Patch Corneal Erosions?, Arch Opgthalmol., vol. 115, 313-317, (Mar. 1997).
A K Brahma, et al., Topical Analgesia For Superficial Corneal Injuries, J Accid Emerg Med, 13:186-188, (1996).
Steve A. Arshinoff, M.D., et al., Pharmacotherapy of Photorefractive Keratectomy, J Cataract Refract Sur, vol. 22, 1037-1044 (Oct. 1996).

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