Topical non-steroidal anti-inflammatory drug composition

Details Topical non-steroidal anti-inflammatory drug composition Topical non-steroidal anti-inflammatory drug composition

1997-09-22

1999-03-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424434, A61K 600, A61K 700, A61F 1300

Patent

active

058885234

ABSTRACT:
A means and method for treating inflamed mucosal tissues topically with a non-steroidal anti-inflammatory drug (NSAID) is described. The NSAID is incorporated into a substantive film forming aqueous based carrier system consisting of a water dispersible natural cellulosic polymer and an organic acid. The NSAID composition may further include a water soluble or water hydratable viscosity enhancing agent and/or a plasticizer. The NSAID topical composition is especially effective in treating pain associated with vulvodynia or vulvar vestibulitis.

REFERENCES:
patent: 4985459 (1991-01-01), Sunshine et al.
patent: 5332576 (1994-07-01), Juan Mantelle
patent: 5665364 (1997-09-01), McAtee et al.
Nov. 5, 1983 pp. 609-612 vol. 6 Obstetrics and Gynecology, Woodruff and Parmley, "Infection of the Minor Vestibular Gland".
Feb. 1987 pp. 110-114 vol. 32 The Journal of Reproductive Medicine, Eduard G. Friedrich, Jr., M.D., LLD., "Vulvar Vestibulitis".
Jun. 1991 pp. 1609-1616 vol. 164 AM J Obstet Gynecol, Martha F. Goetsch, M.D., "Vulvar Vestibulitis, Prevalence and Historic Features In A General Gynecologic Practice Population".

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