Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2005-12-02
2010-11-16
Vu, Jake M. (Department: 1618)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C424S486000
Reexamination Certificate
active
07834059
ABSTRACT:
Topical suspension compositions of nepafenac are disclosed. The compositions are especially suitable for topical ophthalmic administration.
REFERENCES:
patent: 3828093 (1974-08-01), Bays et al.
patent: 4045576 (1977-08-01), Welstead, Jr. et al.
patent: 4126635 (1978-11-01), Welstead, Jr. et al.
patent: 4182774 (1980-01-01), Welstead, Jr. et al.
patent: 4254146 (1981-03-01), Walsh
patent: 4313949 (1982-02-01), Shanklin, Jr. et al.
patent: 4503073 (1985-03-01), Walsh et al.
patent: 4568695 (1986-02-01), Moran et al.
patent: 4683242 (1987-07-01), Poser
patent: 4783487 (1988-11-01), Brune
patent: 4851443 (1989-07-01), Brune
patent: 4910225 (1990-03-01), Ogawa et al.
patent: 5073641 (1991-12-01), Bundgaard et al.
patent: 5461081 (1995-10-01), Ali et al.
patent: 5475034 (1995-12-01), Yanni et al.
patent: 5521222 (1996-05-01), Ali et al.
patent: 5624893 (1997-04-01), Yanni
patent: 6342524 (2002-01-01), Hellberg et al.
patent: 6638976 (2003-10-01), Gamache et al.
patent: 2002/0037929 (2002-03-01), Kapin et al.
patent: 2003/0207941 (2003-11-01), Bingaman et al.
patent: 2005/0239895 (2005-10-01), Sawa et al.
patent: 2 071 086 (1981-09-01), None
patent: 2 093 027 (1982-08-01), None
patent: WO 02/13805 (2002-02-01), None
patent: WO 03/092669 (2003-11-01), None
Penn et al. Studies of the Effect and Mechanism of Action of Topical Nepafenac in Rat Model of ROP. ARVO Annual Meeting, Abstract No. 2741, (2002).
Sancilio et al., “AHR-10037, a non-steroidal anti-inflammatory compound of low gastric toxicity,”Agents and Actions, vol. 31, pp. 117-126 (1990).
Ke et al., “Nepafenac, A Unique Nonsteroidal Prodrug with Potential Utility in the Treatment of Trauma-Induced Ocular Inflammation,”Inflammation, vol. 24(4), pp. 371-384 (2000).
Walsh et al., “Antiinflammatory Agents. 3. Synthesis and Pharmacological Evaluation of 2-Amino-3-benzoyl phenylacetic Acid and Analogues,”J. Med. Chem. vol. 27(11), pp. 1379-1388 (1984).
Walsh et al., “Antiinflammatory Agents. 4. Syntheses and Biological Evaluation of Potential Prodrugs of 2-Amino-3-benzoylbenzeneacetic Acid and 2-Amino-3-(4-chlorobenzoyl)benzeneacetic Acid,”J. Med. Chem., vol. 33, pp. 2296-2304 (1990).
Penn et al., “Studies of the Effect and Mechanism of Action of Topical Nepafenac in a Rat Model of ROP,”ARVO Annual Meeting, Abstract No. 2741, 2002.
Alcon Inc.
Ryan Patrick M.
Vu Jake M.
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