Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1975-04-11
1977-08-02
Ore, Dale R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
424DIG5, 424 47, 424168, 424361, 424365, A01N 928, A61K 3171
Patent
active
040396649
ABSTRACT:
There is disclosed a composition and method for topically administering griseofulvin to a human or animal in a manner such that a high degree of epidermal, especially stratum corneum, retention of griseofulvin is attained, by contacting the skin of a human or animal with an effective amount of a therapeutic composition containing griseofulvin in a vehicle system comprising 2-pyrrolidone and N-methyl-2-pyrrolidone in a ratio ranging between about 1:4 and about 4:1, said composition containing at least about 10% by weight of said vehicle system.
REFERENCES:
patent: 3634586 (1972-01-01), Kaser et al.
patent: 3636194 (1972-01-01), Parizeau
patent: 3932653 (1976-01-01), Stoughton
Beutel, et al., Chem. Abs., 1970, vol. 73, p. 59320q.
Laden, Chem. Abs., 1970, vol. 73, p. 102083d.
Dea Frank J.
Harris Richard L.
Stoughton Richard B.
Nelson Research & Development Company
Ore Dale R.
Voet Martin A.
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