Topical fluoroquinolone antibiotics in an alcohol and acetone ve

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514253, 514254, 514300, 514312, A61K 31535, A61K 31495, A61K 3147, A61K 3144

Patent

active

060179120

ABSTRACT:
A method of treating bacterial infections of the skin comprising topically administering a pharmaceutical composition comprising fluoroquinolones selected from the group consisting of ciprofloxacin, ofloxacin, enoxacin, cinoxacin, pefloxacin, lomefloxacin, norfloxacin, tosufloxacin, fleroxacin, temafloxacin, trovafloxacin and difloxacin, mixed in an alcohol acetone vehicle is disclosed. The topical carrier will be in the form of a cream, ointment, lotion, gel, suspension, emulsion, cleansing bar, pledget, salve, tincture, spray, transdermal device, or other appropriate non-toxic pharmaceutical vehicle.

REFERENCES:
patent: 3944668 (1976-03-01), Cleaver
patent: 4038388 (1977-07-01), Cleaver
patent: 4551456 (1985-11-01), Katz
patent: 5374432 (1994-12-01), Fox et al.
patent: 5401741 (1995-03-01), Sato et al.
patent: 5476854 (1995-12-01), Young
patent: 5648389 (1997-07-01), Gans et al.
Remington' Pharmaceutical Sciences, 15th edition, pp. 1252-1253, 1975.

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