Topical antimicrobial pharmaceutical compositions and methods

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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514558, A61K 3123, A61K 3120

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active

052082571

ABSTRACT:
The present invention discloses a topical antimicrobial and anti-parasite pharmaceutical composition and methods of using the same. The topical antimicrobial pharmaceutical composition includes a safe and effective amount of an ethoxylated or propoxylated glycerol fatty acid ester and a pharmaceutically acceptable carrier. Also disclosed is a topical antimicrobial pharmaceutical composition including a safe and effective amount of a tertiary mixture including, a glycerol fatty acid ester, a binary mixture of fatty acids including a first fatty acid antimicrobial agent selected from C.sub.6 to C.sub.18 fatty acids, and a second fatty acid antimicrobial agent selected from C.sub.6 to C.sub.18 fatty acids, and a pharmaceutically acceptable carrier. Further disclosed is a topical antimicrobial pharmaceutical composition including a safe and effective amount of an ethoxylated or propoxylated glycerol fatty acid ester, a binary fatty acid mixture including, a first fatty acid antimicrobial agent selected from C.sub.6 to C.sub.18 fatty acid and the second fatty acid antimicrobial agent selected from C.sub.6 to C.sub.18 fatty acids, where the second fatty acid is not the same as the first fatty acid, and a pharmaceutically acceptable carrier. Further disclosed is a method of treating and preventing microbial related skin conditions in humans or lower animals comprising topically applying, to the afflicted situs of a human of lower animal in need of such treatment, a safe and effective amount of the above composition.

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