Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1974-10-18
1976-02-10
Rosen, Sam
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
424211, 424212, 424217, 424218, 424224, 424263, A61K 3166, A61K 3144
Patent
active
039378233
ABSTRACT:
Compositions especially useful for treating inflammation topically in animals comprising an active compound having the structural formula ##SPC1##
Where R is H, lower alkyl, lower alkoxy, halogen, CF.sub.3, NO.sub.2, OH, CN, COOR.sub.1, ##EQU1## NHCOR.sub.1 or NR.sub.1 R.sub.2 where R.sub.1 and R.sub.2 are each selected from the group consisting of H and lower alkyl, R, R.sub.1 and R.sub.2 being the same or different, and n is 0-5; and where X is an alkyl or alkenyl chain having 2-8 carbon atoms, one of which carbon atoms may be in the form of a carbonyl group, and Y is hydrogen, alkyl, aryl, aralkyl or aryl and aralkyl substituted with one or more R; and pharmaceutically acceptable salts thereof, together with a pharmaceutical carrier containing an effective amount of an active radical having the structural formula ##SPC2##
Where n is 1-4 and A is H or ##SPC3##
And Z is H or --CH=NOH or --CONHOH and one and only one Z in a heterocyclic ring is H.
REFERENCES:
Goyer et al., Chem. Abst., Vol. 69, (1968), p. 94854f.
Dea Frank Jeng
Schroer Richard Allen
Nelson Research & Development Co.
Rosen Sam
Voet Martin A.
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