Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1994-08-26
1996-10-01
Wityshyn, Michael G.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424 9464, 424 9465, 424 9467, 514611, 514613, 514627, A61K 3846, A61K 3848, A61K 3116, A01N 3306
Patent
active
055609104
ABSTRACT:
The present invention comprises compositions and methods that are useful for topically treating inflammation caused by a wide variety of diseases. The compositions comprise an effective amount of a proteolytic enzyme, such as bromelain, in combination with capsaicin in a pharmaceutically acceptable carrier.
REFERENCES:
patent: 3905869 (1975-09-01), Hidaka et al.
patent: 3932618 (1976-01-01), Fujii et al.
patent: 4507286 (1985-03-01), Vellini
patent: 5178879 (1993-01-01), Adekunle et al.
patent: 5254338 (1993-10-01), Sakai et al.
Taussig, S. J., "The mechanism of the physiological action of Bromelain", Medical Hypotheses, 6: 99-104, 1980.
Hoo-Kyun, C., et al. "Transdermal delivery of bioactive peptides: The Effect of n-Decylmethyl Sulfoxide, pH, and Inhibitors on Enkephalin Metabolism and Transport", Pharm. Res., vol. 7, No. 11, pp. 1099-1106, 1990.
Hoo-Kyun, C., et al. "Some General Influences of n-Decylmethyl Sulfoxide on the Permeation of Drugs Across Hairless Mouse Skin", Soc. Invest. Derm., vol. 96 pp. 822-826, 1991.
Willimann, H., et al., "Lecithin Organogel as Matrix for Transdermal Transport of Drugs", J. Pharm. Sci., vol. 81, 1992.
Scartazzini, et al., J. Phys. Chem., vol. 92, pp. 829-833, 1988.
Luisi, P. L. et al., Colloid Polym Sci., vol. 268, pp. 356-374, 1990.
Colpaert et al. Life Science B2(16). pp. 1827-1834. 1983.
Lam et al. Neurosci Letters 105(1-2) pp. 155-158. 1989.
Lankford L. Blaine
Wityshyn Michael G.
LandOfFree
Topical anti-inflammatory composition and method does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Topical anti-inflammatory composition and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Topical anti-inflammatory composition and method will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1500560