Topical anti-fungal composition for skin and keratinous tissue

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514701, 514724, A61K 31335, A61K 3134, A61K 3111, A61K 31045

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active

054865379

ABSTRACT:
An antifungal composition which can be topically applied to skin and keratinous tissue and is active against the fungi Trichophyton mentagrophytes and Candida albicans includes griseofulvin dissolved in a solvent blend of cinnamic aldehyde and alcohol, particularly isopropanol. Topical antifungal compositions of cinnamic aldehyde in isopropyl alcohol are also provided. Packaged products are provided and include the compositions disposed in sealed containers. A method is also provided for treating keratinous tissue infected with the fungi.

REFERENCES:
CA 87:51751, Bullerman et al., 1977.
CA 117:1440, Liang, 1991.
CA 117:33729, Uhrova et al., 1990.
CA 105:49083, Kamiya et al., 1986.

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