Topical anesthetic formulation

Details Topical anesthetic formulation Topical anesthetic formulation

1998-04-28

1999-11-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424443, 424435, 424485, A61K 600, A61K 700

Patent

active

059938366

ABSTRACT:
A topical, transdermal anesthetic comprising a eutectic mixture of, preferably, lidocaine and prilocaine in a ratio of about 3:1 by weight, incorporated within a lipophilic base. In addition to the property of rapid-onset, the formulation of the present invention has high storage stability and is less restricted by dosage limitations of other prilocaine-containing transdermal anesthetics and is, advantageously, not dependent upon occlusive dressing for optimal transdermal absorption.

REFERENCES:
patent: 4529601 (1985-07-01), Broberg et al.
patent: 4562060 (1985-12-01), Broberg et al.
patent: 5002974 (1991-03-01), Geria
patent: 5332576 (1994-07-01), Mantelle
patent: 5585398 (1996-12-01), Ernst

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